|
INSTITUTE FOR IMMUNOLOGY FACULTY
| Manuela Raffatellu, M.D. |
| Fields of Study: |
| The goal of Dr. Raffatellu’s research is to understand how mucosal responses are orchestrated in response to mucosal pathogens like Salmonella enterica serovar typhimurium. The mucosal immune response has the important function of containing an infection and preventing dissemination of pathogens to systemic sites. However, there is increasing evidence that mucosal pathogens achieve greater colonization during inflammation. Thus, mucosal responses constitute a double-edge sword: on one end, these responses are necessary to contain an infection to the mucosa, and on the other end they favor pathogens colonization. Dr. Raffatellu’s lab is interested in investigating this dichotomy of the host response, and understanding which responses constitute the mucosal barrier during S. typhimurium infection and which ones favor S. typhimurium colonization of the inflamed gut. |
| |
| Research Interests: |
| * |
| |
| Office Address/Phone: |
C135e Med Sci I
(949) 824-0359 |
| |
| Lab Address/Phone: |
C150 Medical Science I
949-824-0457 |
| |
| Email: manuelar@uci.edu |
| Web Site: |
|
|
