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INSTITUTE FOR IMMUNOLOGY FACULTY
| Hung Y. Fan, Ph.D. |
| Fields of Study: |
| Molecular Biology of Retroviruses, Immunology, Cancer Biology, Gene Therapy |
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| Research Interests: |
| Dr. Fan's laboratory is investigating mouse retroviruses, by molecular biological techniques, as model systems for regulation of gene expression, chromatin structure, and carcinogenesis. During infection, retroviruses synthesize a DNA copy of the viral RNA genome using the viral enzyme reverse transcriptase. The viral DNA is then integrated into the host chromosomal DNA. This integrated viral DNA is a complete transcription unit that is transcribed by cellular RNA polymerase. As such, retroviruses offer a convenient system for studying eukaryotic gene expression. Manipulations in viral DNA can be performed by molecular cloning techniques, and the altered viruses can be introduced into cells by DNA transfection |
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| Office Address/Phone: |
106 Sprague Hall, Bldg. 839
949-824-5554 |
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| Lab Address/Phone: |
150 Sprague Hall
949.824.6631 |
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| Email: hyfan@uci.edu |
| Web Site: http://www.faculty.uci.edu/scripts/UCIFacultyProfiles/DetailDept.CFM?ID=2118 |
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